CLDN7 and HGD

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CLDN7	HGD
Description		claudin 7	homogentisate 1,2-dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding	Homogentisate 1,2-dioxygenase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Positive Regulation Of Cell Motility	Cellular Amino Acid Metabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Oxidation-reduction Process
Pathways		Tight junction interactions	Tyrosine catabolism
Drugs
Diseases			Alkaptonuria
GWAS		Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		7 interacting genes: AQP2 EPCAM GLP1R HGD RHOXF2 SYNE4 TJP1	4 interacting genes: CLDN7 GIT2 PCDHGC3 TERF1
Entrez ID		1366	3081
HPRD ID		07633	06315
Ensembl ID		ENSG00000181885	ENSG00000113924
Uniprot IDs		A0A384ME58 F5H496 O95471	B3KW64 Q93099
PDB IDs			1EY2 1EYB
Enriched GO Terms of Interacting Partners?
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