PPARGC1B and ZBTB9

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PPARGC1B	ZBTB9
Description		PPARG coactivator 1 beta	zinc finger and BTB domain containing 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mediator Complex	Nucleus
	Molecular Function	Transcription Coregulator Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Nuclear Receptor Transcription Coactivator Activity AF-2 Domain Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Ossification Regulation Of Transcription, DNA-templated Mitochondrial Transcription Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Cold-induced Thermogenesis
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity
Drugs
Diseases
GWAS		Age spots ( 29895819) Basal cell carcinoma ( 31174203) Freckles ( 29895819) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Nevus count ( 30429480) Nevus count or cutaneous melanoma ( 30429480) Obesity-related traits ( 23251661) Tanning ( 19340012) Vitiligo ( 27723757)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Diastolic blood pressure ( 27841878) Lung cancer ( 28604730)
Interacting Genes		13 interacting genes: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513	31 interacting genes: CAPN7 CHURC1 DTNB DYRK2 EHHADH EIF4E2 GTF2E1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 LASP1 MCM6 MDFI MORF4L1 MYBL2 NFKB1 NR3C1 PARP1 PIN1 PIN4 PPARG PPARGC1B TSR2 ZFP64 ZFY ZKSCAN5 ZNF23 ZNF407 ZNF408 ZZZ3
Entrez ID		133522	221504
HPRD ID		10594	15695
Ensembl ID		ENSG00000155846	ENSG00000213588
Uniprot IDs		B7ZM40 Q86YN6	A0A1U9X8U5 Q96C00
PDB IDs		3SP6 6D0Y
Enriched GO Terms of Interacting Partners?
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