CHMP4B and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 14505570)
373

Data Source:
HPRD (two hybrid)

		CHMP4B	CHMP4C
Description		charged multivesicular body protein 4B	charged multivesicular body protein 4C
Image
GO Annotations	Cellular Component	ESCRT III Complex Cell Nucleus Nuclear Envelope Cytoplasm Endosome Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome	ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Stearic acid (18:0) levels ( 23362303)	Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		15 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PTPN23 STAMBP UBE2I VPS4A	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		128866	92421
HPRD ID		16642	18135
Ensembl ID		ENSG00000101421	ENSG00000164695
Uniprot IDs		Q9H444	Q96CF2
PDB IDs		3C3Q 3UM3 4ABM 5MK2	3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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