MRPL10 and USP22

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)

		MRPL10	USP22
Description		mitochondrial ribosomal protein L10	ubiquitin specific peptidase 22
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit Ribonucleoprotein Complex	SAGA Complex Nucleoplasm SAGA-type Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Translation Ribosome Biogenesis Mitochondrial Translational Elongation Mitochondrial Translational Termination	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 31619474) Body mass index ( 26426971)	Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		8 interacting genes: ACTN2 APP FAM9B KLHL12 PNMA1 REL TCF4 USP22	12 interacting genes: ATXN7 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MYC PSME1 PTGS2 RCAN1 SCFD1 UBC
Entrez ID		124995	23326
HPRD ID		14738	19411
Ensembl ID		ENSG00000159111	ENSG00000124422
Uniprot IDs		Q7Z7H8	Q9UPT9
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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