PIH1D2 and EIF4A2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PIH1D2	EIF4A2
Description		PIH1 domain containing 2	eukaryotic translation initiation factor 4A2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm R2TP Complex Ribonucleoprotein Complex	Cytosol Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ral GTPase Binding	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Box C/D SnoRNP Assembly RRNA Processing	Cytoplasmic Translational Initiation Translational Initiation Regulation Of Translational Initiation Viral Process Negative Regulation Of RNA-directed 5'-3' RNA Polymerase Activity Cellular Response To Leukemia Inhibitory Factor
Pathways			ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: DPH3 EIF4A2 GFAP IGF2BP3 ITGB3BP KRTAP12-4 MDFI MRFAP1L1 MVP RALA REL	19 interacting genes: BRCA1 CLNS1A DPPA4 ECT2 EIF4G1 EIF4G2 GOLGA2 HSPB2 IPO11 MCPH1 MDFI NEK2 PFDN1 PIH1D2 SLC16A9 SSX2IP TK1 TRIM36 TRIM39
Entrez ID		120379	1974
HPRD ID		14021	03062
Ensembl ID		ENSG00000150773	ENSG00000156976
Uniprot IDs		Q8WWB5	Q14240
PDB IDs			3BOR
Enriched GO Terms of Interacting Partners?
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