ANTXR2 and LAMC1

Number of citations of the paper that reports this interaction (PubMedID 11683410)
124

Data Source:
BioGRID (pull down)

		ANTXR2	LAMC1
Description		ANTXR cell adhesion molecule 2	laminin subunit gamma 1
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Laminin-1 Complex Extracellular Space Endoplasmic Reticulum Lumen Laminin-10 Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Constituent Conferring Elasticity
	Biological Process	Reproductive Process Toxin Transport	Cell Adhesion Endoderm Development Animal Organ Morphogenesis Tissue Development Cell Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Hemidesmosome Assembly Substrate Adhesion-dependent Cell Spreading Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Protein-containing Complex Assembly
Pathways			Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Infantile systemic hyalinosis and juvenile hyaline fibromatosis
GWAS		Ankylosing spondylitis ( 21743469 20062062) Bipolar disorder (inflammation and infection response interaction) ( 25781172) Carotid plaque burden ( 28282560) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Hand grip strength ( 29691431) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Myopia ( 27182965) Neutrophil percentage of white cells ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Blood protein levels ( 29875488) Clozapine-induced agranulocytosis ( 25187353) Colorectal cancer ( 23266556) Colorectal cancer or advanced adenoma ( 30510241) Diastolic blood pressure ( 30224653) Fuchs's corneal dystrophy ( 28358029) Height ( 31562340) Hypertriglyceridemia ( 27599772) Systemic lupus erythematosus ( 24871463)
Interacting Genes		10 interacting genes: COL4A2 COL4A3 COL4A4 COL4A5 DDX10 LAMB1 LAMC1 LRP6 RAP1GDS1 SMAD2	14 interacting genes: ANTXR2 APP ATF7IP CENPU LAMA5 NID1 NID2 PSMC5 SNAPIN SNX2 SRPK1 TANK UBC WASHC3
Entrez ID		118429	3915
HPRD ID		07452	01030
Ensembl ID		ENSG00000163297	ENSG00000135862
Uniprot IDs		A4FUA5 J3KPY9 P58335 Q32Q26	P11047 Q6NVY8
PDB IDs		1SHT 1SHU 1T6B 1TZN	5XAU
Enriched GO Terms of Interacting Partners?
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