AP1S1 and AP1M2

Number of citations of the paper that reports this interaction (PubMedID 10535737)
184

Data Source:
HPRD (in vivo)

		AP1S1	AP1M2
Description		adaptor related protein complex 1 subunit sigma 1	adaptor related protein complex 1 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Terminal Bouton Intracellular Membrane-bounded Organelle	Golgi Membrane Cell Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function		Protein Binding
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Retrograde Transport, Endosome To Golgi Regulation Of Defense Response To Virus By Virus	Protein Targeting Vesicle Targeting Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		5 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 RHOU	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		1174	10053
HPRD ID		04635	06296
Ensembl ID		ENSG00000106367	ENSG00000129354
Uniprot IDs		A0A024QYT6 P61966	Q53GI5 Q9Y6Q5
PDB IDs		4P6Z
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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