SSX2IP and DAXX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SSX2IP	DAXX
Description		SSX family member 2 interacting protein	death domain associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Body PML Body
	Molecular Function	Protein Binding Protein Domain Specific Binding	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Enzyme Binding Protein Kinase Binding Protein Kinase Activator Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding SUMO Binding Histone Binding Protein N-terminus Binding Androgen Receptor Binding
	Biological Process	Centrosome Cycle Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility	Positive Regulation Of Protein Phosphorylation Nucleosome Assembly Chromatin Remodeling Regulation Of Transcription, DNA-templated Apoptotic Process Activation Of JUN Kinase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Viral Process Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Heat Cellular Response To Unfolded Protein Regulation Of Apoptotic Process Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Diamide Positive Regulation Of Neuron Death Positive Regulation Of Nucleic Acid-templated Transcription Cellular Response To Sodium Arsenite
Pathways			SUMOylation of transcription cofactors Regulation of TP53 Degradation HCMV Early Events
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)	Autism spectrum disorder or schizophrenia ( 28540026) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)
Interacting Genes		103 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 BCL6 BEX2 BRCA1 BYSL C11orf54 CARD9 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 FAM124B FAM161A FAM214A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF31 PSMA1 RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF3 ZNF417 ZNF587 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12	91 interacting genes: ACVR2A AIRE AR ATM ATRX BTBD6 CA12 CALCOCO2 CARD9 CARM1 CBS CDCA7L CENPC CFLAR CREBBP CSNK2A1 DAPK3 DKC1 DMAP1 DNMT1 ESRRG ETS1 FAM9B FANCA FAS FASLG FTH1 GOLGA2 H3C3 H4-16 H4C6 HABP4 HBA1 HDAC1 HDAC2 HDAC3 HIPK1 HIPK2 HIPK3 HSF1 HSF4 HSPB1 MAP3K5 MCRS1 MDM2 MEN1 MX1 MYH11 NECAB2 NSD3 PARK7 PAX3 PAX5 PBXIP1 PLAGL1 PML PNMA1 PRMT1 PTEN RASSF1 RIPK3 RPL13 SENP2 SERBP1 SLC2A4 SLC9A1 SNW1 SPN SPOP SSX2IP STAT3 STK4 STUB1 SUMO1 SUMO2 SUMO3 TCF3 TCF4 TCF7L2 TGFB1 TGFBR2 TNFRSF1A TP53 TP63 TP73 TRAF3 TRIM21 TSG101 UBC UBE2I USP7
Entrez ID		117178	1616
HPRD ID		10566	04424
Ensembl ID		ENSG00000117155	ENSG00000204209
Uniprot IDs		B7ZB07 Q9Y2D8	A0A024RCS3 B4E1C1 Q53F85 Q9UER7
PDB IDs			2KQS 2KZS 2KZU 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA 5GRQ 5KDM 5Y18 5Y6O
Enriched GO Terms of Interacting Partners?
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