TSEN15 and LMO4

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		TSEN15	LMO4
Description		tRNA splicing endonuclease subunit 15	LIM domain only 4
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Transcription Factor Complex Cell Leading Edge
	Molecular Function	Nucleic Acid Binding Nuclease Activity	Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing Nucleic Acid Phosphodiester Bond Hydrolysis	Neural Tube Closure Ventricular Septum Development Transcription By RNA Polymerase II Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronotype ( 30696823) Height ( 20881960) Hip circumference adjusted for BMI ( 25673412) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in inactive individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		4 interacting genes: EXOSC4 LMO4 NBPF3 TSEN34	53 interacting genes: AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675
Entrez ID		116461	8543
HPRD ID		12292	09122
Ensembl ID		ENSG00000198860	ENSG00000143013
Uniprot IDs		A0A2U3TZM3 B1ALV0 E9PPN1 Q8WW01	P61968
PDB IDs		2GW6	2L4Z
Enriched GO Terms of Interacting Partners?
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