FMNL2 and PNMA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FMNL2	PNMA1
Description		formin like 2	PNMA family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleolus Cytoplasm
	Molecular Function	Rho GTPase Binding Cadherin Binding Actin Filament Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways		RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		5 interacting genes: APP ARL6IP6 CDC42 PNMA1 PRPF40A	131 interacting genes: ABHD17A ANKRD36BP1 APTX ARID5A ASMTL ATP5PO ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CCDC146 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CHIC2 CHMP2B CNNM3 COX5B DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FBF1 FBXL18 FEM1C FMNL2 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HDAC4 HGS HNRNPLL HOXB9 INO80B IVD KANSL1 KAT2B LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 NIF3L1 NPBWR2 NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PIN1 PIN4 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF31 PSMA1 RAPGEF3 RBM41 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TCEANC TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRPV6 TSPYL4 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF410 ZNF564 ZNF581 ZNF688
Entrez ID		114793	9240
HPRD ID		13545	04926
Ensembl ID		ENSG00000157827	ENSG00000176903
Uniprot IDs		Q96PY5	Q8ND90
PDB IDs		4YC7
Enriched GO Terms of Interacting Partners?
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