EFHC1 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		EFHC1	EFHC2
Description		EF-hand domain containing 1	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle	Microtubule
	Molecular Function	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding	Calcium Ion Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Atopic march ( 26542096) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Mean arterial pressure ( 29403010)
Interacting Genes		18 interacting genes: CACNA1E DOK7 EFHC2 EIF4ENIF1 GOLGA2 HOMER3 IHO1 IKZF3 KCTD4 KRT15 REL RIMBP3 SH3GLB2 TCF4 TEX11 TRAF2 TRIP6 ZBED1	37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		114327	80258
HPRD ID		10583	06540
Ensembl ID		ENSG00000096093	ENSG00000183690
Uniprot IDs		B2CKC5 Q5JVL4	Q5JST6
PDB IDs			2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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