CHRNB1 and COPS6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CHRNB1	COPS6
Description		cholinergic receptor nicotinic beta 1 subunit	COP9 signalosome subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Junction Neuromuscular Junction Neuron Projection Synapse Integral Component Of Postsynaptic Specialization Membrane	Nucleoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm
	Molecular Function	Channel Activity Ligand-gated Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding
	Biological Process	Postsynaptic Membrane Organization Skeletal Muscle Contraction Cation Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Response To Nicotine Behavioral Response To Nicotine Regulation Of Membrane Potential Muscle Fiber Development Nervous System Process Excitatory Postsynaptic Potential	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair Viral Process Post-translational Protein Modification
Pathways			DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs		Galantamine
Diseases		Congenital myasthenic syndrome
GWAS		Emotional recognition ( 31596458) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		2 interacting genes: COPS6 RAPSN	86 interacting genes: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COPS9 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 LAMA4 LPL MAP3K1 MAP7D1 MAPK1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24
Entrez ID		1140	10980
HPRD ID		01156	16735
Ensembl ID		ENSG00000170175	ENSG00000168090
Uniprot IDs		P11230	Q7L5N1
PDB IDs			4D10 4D18 4QFT 4R14 4WSN 6R6H 6R7F 6R7H 6R7I
Enriched GO Terms of Interacting Partners?
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