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SYNPO and NCK2
Number of citations of the paper that reports this interaction (PubMedID
24287595
)
13
Data Source:
BioGRID
(pull down)
SYNPO
NCK2
Description
synaptopodin
NCK adaptor protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Cytosol
Bicellular Tight Junction
Postsynaptic Density
Actin Cytoskeleton
Z Disc
Dendritic Spine
Perikaryon
Spine Apparatus
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Cytoplasm
Endoplasmic Reticulum
Cytosol
Vesicle Membrane
Postsynaptic Density
Molecular Function
Actin Binding
Protein Binding
Phosphotyrosine Residue Binding
SH3/SH2 Adaptor Activity
Protein Binding
Cytoskeletal Adaptor Activity
Receptor Signaling Complex Scaffold Activity
Protein-containing Complex Binding
Scaffold Protein Binding
Biological Process
Visual Learning
Positive Regulation Of Actin Filament Bundle Assembly
Regulation Of Long-term Neuronal Synaptic Plasticity
Modification Of Dendritic Spine
Postsynaptic Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Postsynaptic Cytosolic Calcium Concentration
Spine Apparatus Assembly
Immunological Synapse Formation
Actin Filament Organization
Signal Transduction
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Proliferation
Cell Migration
Lamellipodium Assembly
Positive Regulation Of Actin Filament Polymerization
Negative Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Positive Regulation Of T Cell Proliferation
T Cell Activation
Positive Regulation Of Transcription By RNA Polymerase II
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Dendritic Spine Development
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of PERK-mediated Unfolded Protein Response
Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
Downstream signal transduction
Nephrin family interactions
Ephrin signaling
Activation of RAC1
VEGFA-VEGFR2 Pathway
Regulation of cortical dendrite branching
Drugs
Diseases
GWAS
Cholangiocarcinoma in primary sclerosing cholangitis (
28779025
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Medication use (anti-inflammatory and antirheumatic products, non-steroids) (
31015401
)
Addiction (
23533358
)
Platelet distribution width (
27863252
)
Systolic blood pressure in sickle cell anemia (
24058526
)
Interacting Genes
7 interacting genes:
G3BP1
MAGI1
NCK1
NCK2
NONO
YWHAG
YWHAZ
87 interacting genes:
ABI1
ABI2
ABI3
ARHGAP32
ATN1
AXIN1
AXL
BCL11A
CBLB
CCDC33
CD3E
CHN1
CPSF6
CPSF7
DDR1
DNM1
DOCK1
DOK1
DRAP1
DVL1
EEF1G
EFHC2
EFNB1
EFNB2
EFS
EGFR
EIF3H
ERBB2
ERBB3
FAM53C
FASLG
FCRL2
FGFR1
FXR2
FYB1
HNRNPK
HOMEZ
HOXC4
ILK
IRS1
KHDRBS1
KIAA1217
LCP2
LIMS1
LNX1
LRRIQ3
LZTS2
MAGEA6
MASP1
MEOX2
NCKIPSD
NPHS1
NR5A1
NTRK2
PAK1
PDGFRB
PIK3AP1
PKD1
PKN2
PRR20A
PSMD10
PTK2
RASSF7
RBM26
REL
SF3B4
SKAP2
SMARCB1
SORBS2
SOS1
SPRY2
SRPK1
SRPK2
SYNPO
TCF4
TNR
TRIM27
TRIM41
TRIP6
UBC
VARS2
VPS37B
WAS
WASL
WBP11
WIPF2
ZBTB7B
Entrez ID
11346
8440
HPRD ID
12179
05378
Ensembl ID
ENSG00000171992
ENSG00000071051
Uniprot IDs
Q8N3V7
A0A0S2Z4M6
E7ERP6
O43639
PDB IDs
1U5S
1WX6
1Z3K
2B86
2CIA
2FRW
2FRY
2JXB
4E6R
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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