GPN1 and RAB10

		GPN1	RAB10
Description		GPN-loop GTPase 1	RAB10, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Golgi Membrane Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Endomembrane System Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process		Intracellular Protein Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Fasting blood glucose adjusted for BMI ( 25625282) Nonalcoholic fatty liver disease ( 29385134) Oral cavity cancer ( 27749845) Periodontitis (CDC/AAP) ( 24024966) Schizophrenia ( 26198764)	Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Interacting Genes		5 interacting genes: CSNK2A1 MBD2 RAB10 XPA ZBED1	17 interacting genes: APP ATRAID DNAJC27 EFR3B ENOPH1 EVI5L GPN1 IFT172 MICAL1 MTNR1A PLP2 PPBP PREB RABIF RIMS1 SEPTIN9 TP53I3
Entrez ID		11321	10890
HPRD ID		10308	06692
Ensembl ID		ENSG00000198522	ENSG00000084733
Uniprot IDs		Q53RZ9 Q9HCN4	P61026
PDB IDs			5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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