NACC1 and SENP2

Number of citations of the paper that reports this interaction (PubMedID 25891951)
1

Data Source:
BioGRID (enzymatic study)

		NACC1	SENP2
Description		nucleus accumbens associated 1	SUMO specific peptidase 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cell Junction Intracellular Membrane-bounded Organelle	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane
	Molecular Function		Protein Binding SUMO-specific Protease Activity Protein Domain Specific Binding SUMO-specific Endopeptidase Activity SUMO-specific Isopeptidase Activity
	Biological Process	Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Protein Phosphorylation Heart Development Dorsal/ventral Axis Specification Protein Transport Wnt Signaling Pathway Protein Sumoylation Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Negative Regulation Of Protein Binding Regulation Of DNA Endoreduplication Negative Regulation Of Chromatin Binding Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Development Spongiotrophoblast Layer Development Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			SUMO is proteolytically processed
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Diastolic blood pressure ( 28135244 27841878) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) PR interval ( 30046033) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)
Interacting Genes		8 interacting genes: BCOR HDAC3 HDAC4 PML SENP1 SENP2 TARDBP UBE2I	28 interacting genes: AGTRAP APP ARL6IP1 AXIN1 CDCA5 CDK5RAP2 DAXX FUNDC1 FZR1 IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 PML RANGAP1 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TPD52 TRIM63
Entrez ID		112939	59343
HPRD ID		10692	07002
Ensembl ID		ENSG00000160877	ENSG00000163904
Uniprot IDs		A0A024R7E0 Q96RE7	Q9HC62
PDB IDs		3GA1 4U2N	1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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