SNF8 and ELL

Number of citations of the paper that reports this interaction (PubMedID 10419521)
12

Data Source:
HPRD (in vitro)

		SNF8	ELL
Description		SNF8 subunit of ESCRT-II	elongation factor for RNA polymerase II
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Speck Transcriptionally Active Chromatin Histone Locus Body
	Molecular Function	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Phosphatase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex	In Utero Embryonic Development Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Phosphatase Activity Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase III
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Transcription-Coupled Nucleotide Excision Repair (TC-NER) TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)	Alzheimer's disease (late onset) ( 30820047) Breast cancer ( 29059683 23535729) Coronary artery disease ( 29212778) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Pulse pressure ( 30224653)
Interacting Genes		17 interacting genes: ADORA1 CHMP6 DVL2 ELL GOLGA2 HMOX1 KDM1A NIF3L1 PRMT6 RILP SUV39H2 TRIM54 TSG101 VAC14 VPS25 VPS36 YWHAE	11 interacting genes: EAF1 EAF2 HNRNPU MCM2 POLR2A PRKACA SNF8 TFPT TP53 UBC ZHX1
Entrez ID		11267	8178
HPRD ID		16847	02615
Ensembl ID		ENSG00000159210	ENSG00000105656
Uniprot IDs		Q96H20	P55199 U3KQ90
PDB IDs		2ZME 3CUQ	2DOA
Enriched GO Terms of Interacting Partners?
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