STRAP and PBLD

Number of citations of the paper that reports this interaction (PubMedID 11355021)
8

Data Source:
HPRD (two hybrid)

		STRAP	PBLD
Description		serine/threonine kinase receptor associated protein	phenazine biosynthesis like protein domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex	Cytoplasm Extracellular Exosome
	Molecular Function	RNA Binding Signaling Receptor Binding Protein Binding	Molecular_function Protein Binding Isomerase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal SnRNP Assembly Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Biosynthetic Process Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathways		Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS			Optic disc parameters ( 20548946) Optic disc radius ( 31597446) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Optic nerve measurement (disc area) ( 20395239) Vertical cup-disc ratio ( 20548946)
Interacting Genes		24 interacting genes: CHEK2 GEMIN6 GEMIN7 MAP1B MTRES1 NXF1 PBLD PDPK1 RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO4 TGFBR1 TGFBR2	6 interacting genes: CCDC184 EFHC2 LNX1 STRAP TCF4 TRIP13
Entrez ID		11171	64081
HPRD ID		05816	14366
Ensembl ID		ENSG00000023734	ENSG00000108187
Uniprot IDs		B0AZV0 Q9Y3F4	A0A024QZK5 P30039
PDB IDs
Enriched GO Terms of Interacting Partners?
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