GLMN and NSFL1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		GLMN	NSFL1C
Description		glomulin, FKBP associated protein	NSFL1 cofactor
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GO Annotations	Cellular Component	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex	Cell Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex
	Molecular Function	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding
	Biological Process	Vasculogenesis Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Negative Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation Positive Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of Cytokine Secretion	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)
Interacting Genes		11 interacting genes: BIRC2 BIRC3 FBXW7 FKBP1A FKBP4 HSPB1 MET NSFL1C RBX1 RNF7 SKP1	17 interacting genes: ANP32A CDK1 DBI FAM32A FASTKD5 GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP
Entrez ID		11146	55968
HPRD ID		03451	09425
Ensembl ID		ENSG00000174842	ENSG00000088833
Uniprot IDs		B4DJ85 Q92990	Q53FE8 Q9UNZ2
PDB IDs		4F52	1SS6
Enriched GO Terms of Interacting Partners?
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