IL1RAPL1 and NCS1

Number of citations of the paper that reports this interaction (PubMedID 12783849)
27

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		IL1RAPL1	NCS1
Description		interleukin 1 receptor accessory protein like 1	neuronal calcium sensor 1
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Axon Dendrite Postsynaptic Membrane Glutamatergic Synapse	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Cell Junction Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Signaling Receptor Binding Protein Binding Interleukin-1 Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Exocytosis Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Cellular Response To Cytokine Stimulus Presynaptic Membrane Assembly Regulation Of Postsynapse Organization Trans-synaptic Signaling By Trans-synaptic Complex Regulation Of Presynapse Assembly	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling
Drugs			Calcium Citrate Calcium Phosphate
Diseases		Non-syndromic X-linked mental retardation
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Vitiligo ( 27723757)	Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)
Interacting Genes		3 interacting genes: ARHGAP22 NCS1 POLA1	10 interacting genes: DRD2 DRD3 DRD5 DTX2 EXOSC2 GRK2 IL1RAPL1 KCND2 NBL1 PI4KB
Entrez ID		11141	23413
HPRD ID		02193	04500
Ensembl ID		ENSG00000169306	ENSG00000107130
Uniprot IDs		Q9NZN1 X5DNQ7	A0A024R8B2 P62166
PDB IDs		1T3G 4M92 5WY8	1G8I 2LCP 4GUK 5O9S 6QI4
Enriched GO Terms of Interacting Partners?
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