NUP42 and GLE1

Number of citations of the paper that reports this interaction (PubMedID 16000379)
40

Data Source:
BioGRID (x-ray crystallography, biochemical)
HPRD (in vitro, two hybrid)

		NUP42	GLE1
Description		nucleoporin 42	GLE1 RNA export mediator
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Membrane Host Cell	Extracellular Space Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments
	Molecular Function	RNA Binding Nuclear Export Signal Receptor Activity Protein Binding Metal Ion Binding	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding
	Biological Process	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	MRNA Export From Nucleus Regulation Of Translational Initiation Regulation Of Translational Termination Poly(A)+ MRNA Export From Nucleus
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events	Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases			Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)
GWAS			Axial length ( 24144296) Body mass index ( 26426971)
Interacting Genes		3 interacting genes: APC GLE1 NUP214	5 interacting genes: GOLGA2 KRT10 NUP155 NUP42 UXT
Entrez ID		11097	2733
HPRD ID		14855	04536
Ensembl ID		ENSG00000136243	ENSG00000119392
Uniprot IDs		O15504	B3KMG0 Q53GS7
PDB IDs		6B4F 6B4I 6B4J	6B4F 6B4I 6B4J
Enriched GO Terms of Interacting Partners?
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