ADRM1 and UBQLN2

Number of citations of the paper that reports this interaction (PubMedID 18497817)
247

Data Source:
BioGRID (pull down, x-ray crystallography)
HPRD (in vitro)

		ADRM1	UBQLN2
Description		adhesion regulating molecule 1	ubiquilin 2
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GO Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytosol Plasma Membrane Proteasome Regulatory Particle, Lid Subcomplex	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Protease Binding Protein Binding Ubiquitin Binding Endopeptidase Activator Activity Proteasome Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Endopeptidase Activity Protein Deubiquitination Proteasome Assembly	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly
Pathways		UCH proteinases Ub-specific processing proteases	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		21 interacting genes: APP ATP6V0D2 DDI1 EGFR MX1 PRKN PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 SGTA SMURF1 UBC UBE3A UBQLN1 UBQLN2 UCHL5	22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4
Entrez ID		11047	29978
HPRD ID		06440	02224
Ensembl ID		ENSG00000130706	ENSG00000188021
Uniprot IDs		A0A087WX59 Q16186	Q9UHD9
PDB IDs		2KQZ 2KR0 2L5V 2MKZ 2NBV 4UEL 4UEM 4WLQ 4WLR 5IRS 5V1Y 5V1Z 5YMY 6CO4 6OI4	1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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