DSTN and TESK2

Number of citations of the paper that reports this interaction (PubMedID 11418599)
34

Data Source:
HPRD (in vitro)

		DSTN	TESK2
Description		destrin, actin depolymerizing factor	testis associated actin remodelling kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Binding Actin Filament Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing	Protein Phosphorylation Spermatogenesis Peptidyl-tyrosine Phosphorylation Actin Cytoskeleton Organization Focal Adhesion Assembly
Pathways
Drugs		Lauryl Dimethylamine-N-Oxide
Diseases
GWAS		Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)	Blood protein levels ( 28240269) Chronic obstructive pulmonary disease ( 30804561) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean platelet volume ( 27863252) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252)
Interacting Genes		8 interacting genes: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2	3 interacting genes: CFL1 DSTN YWHAB
Entrez ID		11034	10420
HPRD ID		16446	05298
Ensembl ID		ENSG00000125868	ENSG00000070759
Uniprot IDs		P60981 V9HWA6	B4DFN2 Q96S53
PDB IDs
Enriched GO Terms of Interacting Partners?
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