SERINC3 and BMP10

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SERINC3	BMP10
Description		serine incorporator 3	bone morphogenetic protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc
	Molecular Function		Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding
	Biological Process	L-serine Biosynthetic Process Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Detection Of Virus Viral Process Innate Immune Response Defense Response To Virus Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways		Serine biosynthesis	Signaling by BMP Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Bipolar disorder ( 22925353) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		2 interacting genes: BMP10 RPS15	4 interacting genes: ACVR2A ACVR2B BMPR2 SERINC3
Entrez ID		10955	27302
HPRD ID		06201	09788
Ensembl ID		ENSG00000132824	ENSG00000163217
Uniprot IDs		Q13530	O95393
PDB IDs
Enriched GO Terms of Interacting Partners?
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