YIF1A and SLC34A1

Number of citations of the paper that reports this interaction (PubMedID 11099500)
47

Data Source:
HPRD (two hybrid)

		YIF1A	SLC34A1
Description		Yip1 interacting factor homolog A, membrane trafficking protein	solute carrier family 34 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane	Cell Nucleoplasm Endosome Cytosol Plasma Membrane Integral Component Of Plasma Membrane Brush Border Cell Surface Apical Plasma Membrane Nuclear Speck Brush Border Membrane Vesicle Membrane Raft Perinuclear Region Of Cytoplasm Mitotic Spindle
	Molecular Function	Protein Binding	Sodium:phosphate Symporter Activity Protein Binding PDZ Domain Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response	Ossification Kidney Development Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Cellular Phosphate Ion Homeostasis Response To Magnesium Ion Response To Estradiol Response To Vitamin A Phosphate Ion Transmembrane Transport Response To Potassium Ion Indole Metabolic Process Response To Drug Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Phosphate Ion Homeostasis Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Sodium Ion Import Across Plasma Membrane Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport
Pathways		XBP1(S) activates chaperone genes	Type II Na+/Pi cotransporters Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) Surfactant metabolism
Drugs
Diseases			Nephrolithiasis/osteoporosis, hypophosphatemic
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	Activated partial thromboplastin time ( 22703881) Calcium levels ( 24068962) Chronic kidney disease ( 31152163 26831199 20383146) Creatinine levels ( 31015462 28270201 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Hematocrit ( 29403010) Inflammatory bowel disease ( 28067908) Kidney stones ( 26272126 31729369) Nephrolithiasis ( 22396660) Phosphorus levels ( 29403010) Red blood cell count ( 29403010) Serum parathyroid hormone levels ( 27927781) Ulcerative colitis ( 28067908) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: ADAM17 CDK2AP2 GNL1 HEATR1 KAT5 KCNK5 MRPL18 PRIM1 SLC34A1 SLCO2B1 STARD10 STIP1 VKORC1 WDR74 YIPF5 ZDHHC17	11 interacting genes: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PDZK1 PEX19 SLC9A3R1 SLC9A3R2 YIF1A
Entrez ID		10897	6569
HPRD ID		06755	08918
Ensembl ID		ENSG00000174851	ENSG00000131183
Uniprot IDs		A6NGW1 A8K509 O95070	A0A024R7R9 Q06495 Q7Z725 Q86VN6
PDB IDs
Enriched GO Terms of Interacting Partners?
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