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GIPC1 and DDIT3
Number of citations of the paper that reports this interaction (PubMedID
18330356
)
6
Data Source:
BioGRID
(two hybrid)
GIPC1
DDIT3
Description
GIPC PDZ domain containing family member 1
DNA damage inducible transcript 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Brush Border
Cell Cortex
Synaptic Vesicle
Vesicle Membrane
Membrane
Endocytic Vesicle
Cytoplasmic Vesicle
Dendritic Spine
Dendritic Shaft
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Nuclear Chromatin
Cell
Nucleus
Nucleoplasm
Cytoplasm
Late Endosome
Cytosol
Protein-DNA Complex
CHOP-C/EBP Complex
CHOP-ATF4 Complex
CHOP-ATF3 Complex
Molecular Function
Actin Binding
Signaling Receptor Binding
Protein Binding
Myosin Binding
PDZ Domain Binding
Identical Protein Binding
Cadherin Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
CAMP Response Element Binding Protein Binding
Protein Homodimerization Activity
Leucine Zipper Domain Binding
Transcription Regulatory Region DNA Binding
Protein Heterodimerization Activity
Biological Process
Protein Targeting
G Protein-coupled Receptor Signaling Pathway
Chemical Synaptic Transmission
Glutamate Secretion
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Stability
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cytokinesis
Endothelial Cell Migration
Positive Regulation Of Melanin Biosynthetic Process
Regulation Of Synaptic Plasticity
Cellular Response To Interleukin-7
Regulation Of Synaptic Vesicle Exocytosis
Negative Regulation Of Transcription By RNA Polymerase II
Blood Vessel Maturation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cellular Response To DNA Damage Stimulus
ER Overload Response
Response To Unfolded Protein
Cell Cycle Arrest
Regulation Of Autophagy
Wnt Signaling Pathway
Positive Regulation Of Interleukin-8 Production
Negative Regulation Of CREB Transcription Factor Activity
Response To Endoplasmic Reticulum Stress
PERK-mediated Unfolded Protein Response
ATF6-mediated Unfolded Protein Response
Response To Starvation
MRNA Transcription By RNA Polymerase II
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Neuron Apoptotic Process
Regulation Of DNA-templated Transcription In Response To Stress
Regulation Of Transcription Involved In Anterior/posterior Axis Specification
Cell Redox Homeostasis
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Myoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Release Of Sequestered Calcium Ion Into Cytosol
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Establishment Of Protein Localization To Mitochondrion
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Cold-induced Thermogenesis
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress
Negative Regulation Of Determination Of Dorsal Identity
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
ATF6 (ATF6-alpha) activates chaperone genes
FOXO-mediated transcription of cell death genes
FOXO-mediated transcription of cell death genes
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
Myxoid liposarcoma
GWAS
Kidney stones (
31729369
)
Interacting Genes
37 interacting genes:
ACTN1
ADRB1
ARHGEF12
BRD4
CARD10
CD93
DDIT3
DRD2
DRD3
FZD3
GSK3B
IGF1R
ITGA5
ITGA6
KIF1B
LHCGR
LPAR1
LPAR2
LRP1
LRP2
LRP8
MYO6
NRP1
NTRK1
NTRK2
RGS1
RGS19
SDC4
SEMA4B
SEMA4C
SH3BP4
SLC2A1
TGFBR3
TPBG
TYRP1
ZFPM1
ZNF408
61 interacting genes:
AMOTL2
ATF2
ATF3
ATF4
ATPAF2
BACH1
BACH2
BATF
BATF2
BATF3
CCDC153
CDK6
CEBPA
CEBPB
CEBPE
CEBPG
CREB3
CREB3L1
CSNK2A1
DBP
DGCR2
DNMT3L
EMSY
EP300
EPAS1
F2
FOS
FOSL1
FOSL2
GIPC1
GP1BA
HOXA5
HSD17B14
IKBKG
JUN
JUNB
JUND
KPNA2
LMO2
MAFF
MAFG
MAPK14
MCMBP
NFIL3
PCM1
PICALM
POLR1D
RAI1
RPS3
RPS3A
SNAPC5
SPOP
SRA1
SSX3
TEDC1
TNFSF12
TRIB3
VPS37C
ZBTB25
ZC3H14
ZSCAN31
Entrez ID
10755
1649
HPRD ID
05462
00529
Ensembl ID
ENSG00000123159
ENSG00000175197
Uniprot IDs
A0A024R7I0
A0A024R7I1
A8K2I7
O14908
P35638
Q53YD1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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