PLK4 and ARR3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLK4	ARR3
Description		polo like kinase 4	arrestin 3
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GO Annotations	Cellular Component	Spindle Pole XY Body Nucleus Nucleolus Cytoplasm Centrosome Centriole Cytosol Cleavage Furrow Deuterosome	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Phosphorylation Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cytokinesis Positive Regulation Of Centriole Replication Trophoblast Giant Cell Differentiation Ciliary Basal Body-plasma Membrane Docking De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation	Regulation Of Protein Phosphorylation G Protein-coupled Receptor Internalization Signal Transduction Visual Perception
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
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Diseases
GWAS
Interacting Genes		12 interacting genes: ARR3 BTRC C1orf109 CHD3 ELOA MTUS2 SFN SMAD4 TAX1BP3 TEC TENT5C TGFBR1	19 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		10733	407
HPRD ID		10387	02358
Ensembl ID		ENSG00000142731	ENSG00000120500
Uniprot IDs		O00444	P36575
PDB IDs		2N19 3COK 4JXF 4N7V 4N7Z 4N9J 4YUR 4YYP 5LHY 5LHZ 6N45 6N46	1XEH 2A34
Enriched GO Terms of Interacting Partners?
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