PTGES3 and AIP

Number of citations of the paper that reports this interaction (PubMedID 11259606)
39

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		PTGES3	AIP
Description		prostaglandin E synthase 3	aryl hydrocarbon receptor interacting protein
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Cytoplasm Cytosol Protein-containing Complex Chaperone Complex	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Aryl Hydrocarbon Receptor Complex
	Molecular Function	Telomerase Activity Protein Binding Prostaglandin-E Synthase Activity Unfolded Protein Binding Chaperone Binding Hsp90 Protein Binding DNA Polymerase Binding	Transcription Coactivator Activity Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding GAF Domain Binding Unfolded Protein Binding
	Biological Process	Telomere Maintenance Prostaglandin Biosynthetic Process Protein Folding Xenobiotic Metabolic Process Telomere Maintenance Via Telomerase Signal Transduction Cyclooxygenase Pathway Positive Regulation Of Phosphorylation Protein Stabilization Chaperone Cofactor-dependent Protein Refolding Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity Regulation Of Cellular Response To Heat Telomerase Holoenzyme Complex Assembly	Protein Peptidyl-prolyl Isomerization Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Regulation Of Protein Kinase A Signaling Protein Maturation By Protein Folding Interleukin-12-mediated Signaling Pathway Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) HSP90 chaperone cycle for steroid hormone receptors (SHR) HSF1 activation Attenuation phase Aryl hydrocarbon receptor signalling ESR-mediated signaling Estrogen-dependent gene expression	Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Grn163l Copper
Diseases
GWAS		Asthma ( 31619474) High light scatter reticulocyte percentage of red cells ( 27863252) Mean platelet volume ( 22139419) Platelet count ( 22139419)	Urate levels ( 31578528)
Interacting Genes		29 interacting genes: AHR AHSA1 AIP ARNT CASP3 CASP7 CAV3 CD2AP CDC37 COPG1 COPG2 DNAJB1 DNMT3A EIF2AK2 ERBB3 ESR1 FES GZMB HSF1 HSP90AA1 HSP90AB1 HSPA1A HSPB1 NR3C1 NR3C2 STIP1 SURF1 TERT THRA	16 interacting genes: AHR ARNT CLEC7A CSNK2A1 EGFR GNA13 GNAQ HSP90AA1 IKBKG IRF7 PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20
Entrez ID		10728	9049
HPRD ID		06138	10408
Ensembl ID		ENSG00000110958	ENSG00000110711
Uniprot IDs		A0A024RB32 A0A087WYT3 B3KUY2 Q15185	G9I2H4 O00170
PDB IDs		1EJF 1LG0	2LKN 4AIF 4APO
Enriched GO Terms of Interacting Partners?
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