FARS2 and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FARS2	CMTM5
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	CKLF like MARVEL transmembrane domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Extracellular Space Integral Component Of Membrane
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Cytokine Activity Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways		Mitochondrial tRNA aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
Interacting Genes		23 interacting genes: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NLA RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		10667	116173
HPRD ID		09946	06986
Ensembl ID		ENSG00000145982	ENSG00000166091
Uniprot IDs		O95363	Q96DZ9
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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