PAICS and SMARCD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PAICS	SMARCD1
Description		phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex
	Molecular Function	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity
	Biological Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid
Pathways		Purine ribonucleoside monophosphate biosynthesis	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		L-Aspartic Acid
Diseases
GWAS			Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		11 interacting genes: CEP76 CHD3 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PRKAG1 SMARCD1 TERF1	50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		10606	6602
HPRD ID		01401	03438
Ensembl ID		ENSG00000128050	ENSG00000066117
Uniprot IDs		P22234	Q96GM5
PDB IDs		2H31
Enriched GO Terms of Interacting Partners?
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