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LAMTOR5 and LAMTOR4
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
LAMTOR5
LAMTOR4
Description
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Image
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Cytosol
Ragulator Complex
Lysosome
Lysosomal Membrane
Intracellular Membrane-bounded Organelle
Ragulator Complex
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Molecular Adaptor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Molecular Adaptor Activity
Biological Process
Cell Cycle Arrest
Regulation Of Cell Size
Response To Virus
Positive Regulation Of Gene Expression
Regulation Of Macroautophagy
Viral Genome Replication
Positive Regulation Of TOR Signaling
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Interleukin-8 Biosynthetic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of TORC1 Signaling
Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Cell Cycle Arrest
Regulation Of Cell Size
Regulation Of Macroautophagy
Positive Regulation Of TOR Signaling
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Pathways
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription
Amino acids regulate mTORC1
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription
Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes
32 interacting genes:
ALB
ASGR1
BHMT
C9
CD74
CEP126
CEP70
CFB
CLCC1
DBI
EEF1A1
GAPDH
GIT1
GPRASP1
LAMTOR4
LRIF1
MAF1
MCPH1
MEOX2
MT2A
NCOA6
PDK1
RABIF
RBP4
SERPINA1
TAF9
TGFB1
TOP2B
TP53
UTP14A
YTHDC1
ZBTB16
2 interacting genes:
LAMTOR5
USP19
Entrez ID
10542
389541
HPRD ID
09773
17380
Ensembl ID
ENSG00000134248
ENSG00000188186
Uniprot IDs
A0A0C4DGV4
O43504
A0A087WT92
A0A087WV46
Q0VGL1
PDB IDs
3MS6
3MSH
5VOK
5X6U
5X6V
5Y38
5Y39
5Y3A
5YK3
6B9X
6EHP
6EHR
6NZD
6U62
6ULG
5VOK
5X6U
5X6V
5Y38
5Y39
5Y3A
5YK5
6B9X
6EHP
6EHR
6NZD
6U62
6ULG
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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