DCTN2 and BICD2

Number of citations of the paper that reports this interaction (PubMedID 11483508)
97

Data Source:
HPRD (in vitro, in vivo)

		DCTN2	BICD2
Description		dynactin subunit 2	BICD cargo adaptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Cell Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome	Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Motor Activity Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding	Protein Binding Cytoskeletal Adaptor Activity Rab GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle ER To Golgi Vesicle-mediated Transport Mitotic Spindle Organization Mitotic Metaphase Plate Congression Regulation Of G2/M Transition Of Mitotic Cell Cycle Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Transport Protein Localization To Centrosome Ciliary Basal Body-plasma Membrane Docking	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Protein Transport Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center
Pathways		MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2	COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Height ( 31562340) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		22 interacting genes: BICD1 BICD2 BLOC1S6 CALM1 CCDC172 DISC1 EGFR GADD45A GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 PAFAH1B1 RPGR ZW10	5 interacting genes: DCTN1 DCTN2 GSK3B NEK9 RAB6A
Entrez ID		10540	23299
HPRD ID		09568	09826
Ensembl ID		ENSG00000175203	ENSG00000185963
Uniprot IDs		A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58	Q8TD16 Q96FU2
PDB IDs			6OFP
Enriched GO Terms of Interacting Partners?
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