STK25 and PDCD10

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		STK25	PDCD10
Description		serine/threonine kinase 25	programmed cell death 10
Image
GO Annotations	Cellular Component	Golgi Membrane Cell Cytoplasm Golgi Apparatus Extracellular Exosome	Golgi Membrane Cell Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Regulation Of Mitotic Cell Cycle Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly	Angiogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases			Cerebral cavernous malformation
GWAS		Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)	Fast beta electroencephalogram ( 28070124)
Interacting Genes		16 interacting genes: APP CCNDBP1 CEP70 GOLGA2 HDAC2 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17	5 interacting genes: CHMP5 RHOA STK24 STK25 STK26
Entrez ID		10494	11235
HPRD ID		03770	10141
Ensembl ID		ENSG00000115694	ENSG00000114209
Uniprot IDs		A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2	C9J363 Q9BUL8
PDB IDs		2XIK 3W8H 4NZW	3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ
Enriched GO Terms of Interacting Partners?
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