LRRC41 and MYO9B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRRC41	MYO9B
Description		leucine rich repeat containing 41	myosin IXB
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane	Cytoplasm Cytosol Actin Filament Cell Cortex Actin Cytoskeleton Membrane Myosin Complex Perinuclear Region Of Cytoplasm
	Molecular Function		Microfilament Motor Activity Actin Binding GTPase Activator Activity Protein Binding Calmodulin Binding ATP Binding ATPase Activity Rho GTPase Binding Protein Homodimerization Activity ADP Binding Metal Ion Binding Roundabout Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification	Rho Protein Signal Transduction Actin Filament-based Movement ARF Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Roundabout Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation SLIT2:ROBO1 increases RHOA activity FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878) Glycated hemoglobin levels ( 24647736 28898252) Height ( 20881960 31562340 29782485) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Night sleep phenotypes ( 27126917) Platelet count ( 29403010 27863252) Plateletcrit ( 27863252) Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Selective IgA deficiency ( 27723758) Systolic blood pressure ( 27841878 30578418) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		4 interacting genes: ELOB ELOC MYO9B RBPMS	7 interacting genes: ACTA1 ARFGEF1 CALM1 LRRC41 MOB4 PKN2 RAB8A
Entrez ID		10489	4650
HPRD ID		10102	03677
Ensembl ID		ENSG00000132128	ENSG00000099331
Uniprot IDs		Q15345	B0I1T6 Q13459 Q4LE74 Q8WVD2
PDB IDs			5C5S 5HPY
Enriched GO Terms of Interacting Partners?
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