SEC23B and DTX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC23B	DTX2
Description		SEC23 homolog B, COPII coat complex component	deltex E3 ubiquitin ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle	Notch Signaling Pathway Protein Ubiquitination
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS
Interacting Genes		21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1	44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641
Entrez ID		10483	113878
HPRD ID		11543	16841
Ensembl ID		ENSG00000101310	ENSG00000091073
Uniprot IDs		A0A2R8YFH5 Q15437	Q86UW9
PDB IDs			6IR0
Enriched GO Terms of Interacting Partners?
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