TRIM38 and TSPYL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM38	TSPYL4
Description		tripartite motif containing 38	TSPY like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity	Protein Binding
	Biological Process	Regulation Of Interferon-beta Production Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Defense Response To Virus Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Protein K48-linked Ubiquitination	Nucleosome Assembly
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cardiac hypertrophy ( 21348951) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)	Fast beta electroencephalogram ( 28040410) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: ATXN1 EIF1B GMCL1 GORASP2 HSPA1A HSPA2 HSPA8 RFC5 RIPK1 SDCBP STXBP1 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U	8 interacting genes: CCDC85B CDK5RAP3 CELSR3 NAP1L3 NINL PNMA1 TFIP11 TRIM38
Entrez ID		10475	23270
HPRD ID		15555	18236
Ensembl ID		ENSG00000112343	ENSG00000187189
Uniprot IDs		A0A024QZY4 O00635	Q9UJ04
PDB IDs
Enriched GO Terms of Interacting Partners?
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