CLGN and ADAM2

Number of citations of the paper that reports this interaction (PubMedID 11784061)
28

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CLGN	ADAM2
Description		calmegin	ADAM metallopeptidase domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity
	Biological Process	Protein Folding Single Fertilization Binding Of Sperm To Zona Pellucida Endoplasmic Reticulum Unfolded Protein Response Protein-containing Complex Assembly	Proteolysis Cell Adhesion Binding Of Sperm To Zona Pellucida Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Visual Learning Positive Regulation Of Gene Expression Adult Behavior
Pathways			Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Diastolic blood pressure x sodium interaction (2df test) ( 27271309) Mean arterial pressure x sodium interaction (2df test) ( 27271309) Select biomarker traits ( 17903293) Systolic blood pressure x sodium interaction (2df test) ( 27271309)	Restless legs syndrome ( 29029846)
Interacting Genes		4 interacting genes: ADAM2 GDE1 LINC00839 XK	2 interacting genes: CD9 CLGN
Entrez ID		1047	2515
HPRD ID		03513	03322
Ensembl ID		ENSG00000153132	ENSG00000104755
Uniprot IDs		A0A140VKG2 O14967	B4DWY7 Q6P2G0 Q99965
PDB IDs
Enriched GO Terms of Interacting Partners?
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