PIBF1 and CEP135

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (proximity labelling technology, affinity chromatography technology, two hybrid)

		PIBF1	CEP135
Description		progesterone immunomodulatory binding factor 1	centrosomal protein 135
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cell Nucleus Cytoplasm Centrosome Centriolar Satellite	Centrosome Centriole Cytosol
	Molecular Function	Interleukin-4 Receptor Binding Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Immune System Process Mitotic Metaphase Plate Congression Negative Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Negative Regulation Of Natural Killer Cell Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Activation Of Janus Kinase Activity Cilium Assembly Protein Localization To Centrosome Mitotic Spindle Assembly Non-motile Cilium Assembly	G2/M Transition Of Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Centriole-centriole Cohesion Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Non-motile Cilium Assembly Positive Regulation Of Establishment Of Protein Localization
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Blood pressure measurement (low sodium intervention) ( 24165912) Mean corpuscular hemoglobin ( 27863252) Waist circumference ( 28552196)	Bone mineral density (hip) ( 30172743) Daytime sleep phenotypes ( 27126917) Femoral neck bone mineral density ( 30172743) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: APP CEP135 CEP70 HAUS1 MAP3K2	7 interacting genes: CLOCK DCUN1D4 PIBF1 REST SMAD9 SPINK2 USP46
Entrez ID		10464	9662
HPRD ID		06337	11097
Ensembl ID		ENSG00000083535	ENSG00000174799
Uniprot IDs		Q8WXW3	Q66GS9
PDB IDs			5FCN 5NG4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?