CDC42EP2 and SEPTIN7

Number of citations of the paper that reports this interaction (PubMedID 11584266)
73

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CDC42EP2	SEPTIN7
Description		CDC42 effector protein 2	septin 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Condensed Chromosome Kinetochore Stress Fiber Nucleus Spindle Cytosol Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Cell Division Site Cleavage Furrow Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding GTP-Rho Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of GTPase Activity Cellular Response To Interferon-gamma	Spermatogenesis Regulation Of Embryonic Cell Shape Cell Differentiation Negative Regulation Of Cell Migration Cellular Protein Localization Positive Regulation Of Apoptotic Process Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		MAPK6/MAPK4 signaling	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular volume ( 27863252)
Interacting Genes		7 interacting genes: ARHGAP26 CDC42 NME7 RHOQ SEPTIN6 SEPTIN7 SNCA	12 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE HDAC6 REL S100A4 SEPTIN10 SEPTIN11 SEPTIN5 SEPTIN9
Entrez ID		10435	989
HPRD ID		09363	04398
Ensembl ID		ENSG00000149798	ENSG00000122545
Uniprot IDs		O14613	A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181
PDB IDs			2QAG 3T5D 3TW4 6N0B 6N12
Enriched GO Terms of Interacting Partners?
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