DLEU1 and GDF9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLEU1	GDF9
Description		deleted in lymphocytic leukemia 1	growth differentiation factor 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Cytoplasm
	Molecular Function		Cytokine Activity Growth Factor Activity
	Biological Process		Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases
GWAS		Adiponectin levels ( 26299439) Adiponectin levels (BMI-adjusted) ( 26299439) Aluminium levels ( 26025379) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163) Circulating odd-numbered chain saturated fatty acid levels (C19:0) ( 29738550) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 31562340 31217584) Hematocrit ( 29403010) Hemoglobin ( 29403010) Hip circumference adjusted for BMI ( 28552196) Lipoprotein (a) levels ( 30108283) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244 21833088 27386562) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376) Plasma anti-thyroid peroxidase levels ( 29678681) Primary biliary cholangitis ( 26394269) Prostate-specific antigen levels ( 28139693) Triglycerides ( 30275531) Tumor necrosis factor alpha levels ( 31217265) Type 2 diabetes ( 30054458 30297969) Urinary albumin-to-creatinine ratio ( 31630189) Urinary magnesium excretion ( 31993563) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196) Weight ( 28552196)	Asthma ( 31619474)
Interacting Genes		20 interacting genes: ABCD4 ABCF3 ARL8B CCDC90B CEP126 COPS6 EEF1A1 EEF1G GDF9 GOPC KAT5 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3
Entrez ID		10301	2661
HPRD ID		16150	03560
Ensembl ID		ENSG00000176124	ENSG00000164404
Uniprot IDs			B4DXG3 O60383
PDB IDs
Enriched GO Terms of Interacting Partners?
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