TRAIP and MAPRE2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAIP	MAPRE2
Description		TRAF interacting protein	microtubule associated protein RP/EB family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Perinuclear Region Of Cytoplasm	Cytoplasm Microtubule Organizing Center Microtubule Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Apoptotic Process Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Protein Localization To Microtubule Positive Regulation Of GTPase Activity Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly Protein Localization To Microtubule Plus-end
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) C-reactive protein levels ( 30388399) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Tea consumption ( 31046077)	Cerebrospinal fluid AB1-42 levels ( 26252872) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APP CYLD FLII MAGEF1 MAPRE2 PCNA POLK RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2	24 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 FBXO7 GTSE1 LMNA LMO2 MAPRE1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Entrez ID		10293	10982
HPRD ID		05811	16157
Ensembl ID		ENSG00000183763	ENSG00000166974
Uniprot IDs		Q9BWF2	A0A024RC33 Q15555
PDB IDs		4ZTD
Enriched GO Terms of Interacting Partners?
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