RBM12 and PRMT2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		RBM12	PRMT2
Description		RNA binding motif protein 12	protein arginine methyltransferase 2
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GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process		Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Diverticular disease ( 30177863)
Interacting Genes		5 interacting genes: BRAP GIGYF2 OPTN PRMT2 TBC1D4	23 interacting genes: BAG6 CBLB CHEK2 CPSF7 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRRC2A PSMB3 RB1 RBM12 RIPK2 RXRA SPAG8 THRB WASL ZNF341
Entrez ID		10137	3275
HPRD ID		06212	09060
Ensembl ID		ENSG00000244462	ENSG00000160310
Uniprot IDs		Q9NTZ6	A0A0S2Z3N3 P55345
PDB IDs		1WEL 2CPY 2DNN 2EK1 2EK6	1X2P
Enriched GO Terms of Interacting Partners?
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