CERT1 and ACTL8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CERT1	ACTL8
Description		ceramide transporter 1	actin like 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Actin Filament Presynapse
	Molecular Function	Protein Binding Lipid Binding Kinase Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding Intermembrane Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity	Protein Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Phosphorylation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Mitochondrion Morphogenesis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport	Epithelial Cell Differentiation Synaptic Vesicle Endocytosis Postsynaptic Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 31219225) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		11 interacting genes: ACTL8 AQP2 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2	2 interacting genes: CERT1 UBC
Entrez ID		10087	81569
HPRD ID		05246	11274
Ensembl ID		ENSG00000113163	ENSG00000117148
Uniprot IDs		A0A024RAJ5 A0A2R8Y7C5 Q9Y5P4	Q9H568
PDB IDs		2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81
Enriched GO Terms of Interacting Partners?
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