CDH3 and CTNNA1

Number of citations of the paper that reports this interaction (PubMedID 1924379)
99

Data Source:
HPRD (in vivo)

		CDH3	CTNNA1
Description		cadherin 3	catenin alpha 1
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Adherens Junction Cell Surface Integral Component Of Membrane Catenin Complex Cell Junction	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Flotillin Complex Lamellipodium Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Calcium Ion Binding Cytoskeletal Protein Binding Cadherin Binding	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Identical Protein Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Cell Morphogenesis Retina Homeostasis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Visual Perception Positive Regulation Of Gene Expression Positive Regulation Of Keratinocyte Proliferation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Hair Cycle Process Keratinization Positive Regulation Of Monophenol Monooxygenase Activity Negative Regulation Of Transforming Growth Factor Beta2 Production Adherens Junction Organization Wound Healing Response To Drug Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Melanin Biosynthetic Process Negative Regulation Of Timing Of Catagen Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Positive Regulation Of Melanosome Transport	Ovarian Follicle Development Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Axon Regeneration Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Adherens junctions interactions	Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs
Drugs
Diseases		Hypotrichosis, congenital, with juvenile macular dystrophy Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)
GWAS		Glycated hemoglobin levels ( 28898252) Multiple sclerosis ( 31604244 24076602) Red cell distribution width ( 27863252) Ulcerative colitis ( 28067908)	General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061)
Interacting Genes		3 interacting genes: CTNNA1 CTNNB1 CTNND1	31 interacting genes: ACTN1 AFDN AJUBA APC APP ARMC8 CA9 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 DLG1 JUP LRATD2 MTNR1A MTNR1B OBI1 PKD1 PSEN1 SASH1 SPTAN1 SPTBN1 TJP1 TJP2 UBE2I VCL ZGPAT
Entrez ID		1001	1495
HPRD ID		00227	00285
Ensembl ID		ENSG00000062038	ENSG00000044115
Uniprot IDs		B4DLF0 P22223	A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221
PDB IDs		4OY9 4ZML 4ZMN 4ZMO 4ZMP 4ZMQ 4ZMT 4ZMV 4ZMW 4ZMX 4ZMY 4ZMZ 5JYL 5JYM	1H6G 4EHP 4IGG
Enriched GO Terms of Interacting Partners?
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