NRXN3

Description		neurexin 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding Neuroligin Family Protein Binding
	Biological Process	Neuron Cell-cell Adhesion Axon Guidance Learning Adult Behavior Social Behavior Vocalization Behavior
Pathways		Neurexins and neuroligins Neurexins and neuroligins Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728) Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28552196 26865924 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Bone mineral density (hip) ( 30172743) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) Electrodermal activity ( 25387706) Figural/spatial cognitive ability ( 31620175) Hip circumference ( 25673412) JT interval (sulfonylurea treatment interaction) ( 27958378) Medial orbital frontal cortex volume ( 31530798) Normal facial asymmetry (angle of deformation score) ( 30631343) Obesity ( 23563607 21552555) Objective response to lithium treatment in bipolar disorder ( 26503763) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proliferative diabetic retinopathy in type 2 diabetes ( 29739359) Response to antidepressants (symptom improvement) ( 29160301) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573) Rosacea symptom severity ( 29771307) Schizophrenia ( 30285260) Tea consumption ( 31046077) Type 2 diabetes ( 28566273 30054458 30297969) Underweight status ( 25133637) Urinary sodium excretion ( 31409800) Waist circumference ( 19557197 25673412) Waist-hip ratio ( 25673412) Weight ( 28552196)
Interacting Genes		6 interacting genes: AFDN CASK DNAJC5 NLGN1 NLGN2 NLGN3
Entrez ID		9369
HPRD ID		08989
Ensembl ID		ENSG00000021645
Uniprot IDs		A0A0U1RRJ0 Q9HDB5 Q9Y4C0
PDB IDs
Enriched GO Terms of Interacting Partners?
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