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MYOCD
Description
myocardin
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Histone Acetyltransferase Binding
Histone Deacetylase Binding
RNA Polymerase II Sequence-specific DNA-binding Transcription Factor Binding
R-SMAD Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth By Extracellular Stimulus
Vasculogenesis
Response To Hypoxia
Cardiac Ventricle Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Positive Regulation Of Cell Proliferation
Negative Regulation Of Cell Proliferation
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Myotube Differentiation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cardiocyte Differentiation
Regulation Of Histone Acetylation
Vascular Smooth Muscle Cell Differentiation
Positive Regulation Of DNA Binding
Cellular Component Maintenance
Regulation Of Myoblast Differentiation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Smooth Muscle Contraction
Lung Alveolus Development
Digestive Tract Development
Positive Regulation Of DNA-binding Transcription Factor Activity
Smooth Muscle Cell Differentiation
Regulation Of Smooth Muscle Cell Differentiation
Positive Regulation Of Smooth Muscle Cell Differentiation
Cardiac Muscle Cell Differentiation
Ventricular Cardiac Muscle Cell Differentiation
Uterus Development
Urinary Bladder Development
Ductus Arteriosus Closure
Negative Regulation Of Amyloid-beta Clearance
Regulation Of Phenotypic Switching
Negative Regulation Of Vascular Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Positive Regulation Of Cardiac Muscle Cell Differentiation
Negative Regulation Of Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
29892015
)
Metabolite levels (
23823483
)
PR interval (
30679814
30046033
)
QRS duration (
31251759
)
Systolic blood pressure change trajectories (
27980656
)
Testosterone levels (
22675492
)
Interacting Genes
11 interacting genes:
GOPC
GSK3B
KDM3A
MAMSTR
MRTFA
MYOD1
SMAD2
SMAD3
SMARCA4
SRF
STUB1
Entrez ID
93649
HPRD ID
09362
Ensembl ID
ENSG00000141052
Uniprot IDs
Q8IZQ8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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