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DDX21

Description DExD-box helicase 21
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Nucleolus
  • Mitochondrion
  • Cytosol
  • Membrane
Molecular Function
  • RNA Binding
  • RNA Helicase Activity
  • Double-stranded RNA Binding
  • Protein Binding
  • ATP Binding
  • RRNA Binding
  • SnoRNA Binding
  • MiRNA Binding
  • Identical Protein Binding
  • 7SK SnRNA Binding
Biological Process
  • Osteoblast Differentiation
  • Positive Regulation Of Myeloid Dendritic Cell Cytokine Production
  • RRNA Processing
  • Transcription By RNA Polymerase II
  • Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
  • Response To Exogenous DsRNA
  • Innate Immune Response
  • Positive Regulation Of Gene Expression, Epigenetic
  • Defense Response To Virus
Pathways
  • B-WICH complex positively regulates rRNA expression
  • Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
  • Depression (quantitative trait) ( 20800221)
Interacting Genes 18 interacting genes: ADAMTS14 CALM1 CSNK2A1 ERG H2AX IL7R JUN KPNA3 MTHFR PIAS1 PNMA2 SGPL1 SRPK2 SUMO2 TERF1 TERF2 TET1 UBE2I
Entrez ID 9188
HPRD ID 05895
Ensembl ID ENSG00000165732
Uniprot IDs Q9NR30
PDB IDs 2M3D
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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