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DPM1

Description dolichyl-phosphate mannosyltransferase subunit 1, catalytic
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Dolichol-phosphate-mannose Synthase Complex
Molecular Function
  • Dolichyl-phosphate-mannose-protein Mannosyltransferase Activity
  • Dolichyl-phosphate Beta-D-mannosyltransferase Activity
  • Protein Binding
Biological Process
  • GPI Anchor Biosynthetic Process
  • Protein N-linked Glycosylation Via Asparagine
  • Dolichol Metabolic Process
  • Protein Mannosylation
  • Protein O-linked Mannosylation
Pathways
  • Synthesis of dolichyl-phosphate mannose
  • Defective DPM1 causes DPM1-CDG (CDG-1e)
  • Defective DPM3 causes DPM3-CDG (CDG-1o)
  • Defective DPM2 causes DPM2-CDG (CDG-1u)
Drugs
Diseases
  • Congenital disorders of glycosylation (CDG) type I
GWAS
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
Interacting Genes 5 interacting genes: DPM2 DPM3 MTNR1A TDO2 ZBTB16
Entrez ID 8813
HPRD ID 04613
Ensembl ID ENSG00000000419
Uniprot IDs A0A0S2Z4Y5 O60762 Q5QPK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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