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CBR1

Description carbonyl reductase 1
Image
GO Annotations Cellular Component
  • Cytosol
  • Extracellular Exosome
  • Extracellular Vesicle
Molecular Function
  • Carbonyl Reductase (NADPH) Activity
  • Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor
  • 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity
  • Prostaglandin-E2 9-reductase Activity
Biological Process
  • Drug Metabolic Process
  • Cyclooxygenase Pathway
  • Epithelial Cell Differentiation
  • Vitamin K Metabolic Process
  • Oxidation-reduction Process
Pathways
  • Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
  • Rutin
  • Resveratrol
  • 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400
  • Quercetin
  • 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol
  • Curcumin
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Metabolite levels ( 23823483)
  • Mitral valve prolapse ( 26301497)
Interacting Genes 6 interacting genes: EGFR ERCC8 PRKAR2B PTPRF UBC VHL
Entrez ID 873
HPRD ID 00267
Ensembl ID ENSG00000159228
Uniprot IDs A0A384NL53 P16152
PDB IDs 1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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