SMARCD3

Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex NpBAF Complex NBAF Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Transcription Factor Binding Nuclear Hormone Receptor Binding
	Biological Process	Positive Regulation Of Neuroblast Proliferation Secondary Heart Field Specification Cardiac Right Ventricle Formation Neural Retina Development Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Lipid Metabolic Process Muscle Cell Differentiation Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Smooth Muscle Cell Differentiation
Pathways		RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Heel bone mineral density ( 30598549) IgG glycosylation ( 23382691) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Multiple myeloma ( 27363682)
Interacting Genes		20 interacting genes: ARHGAP1 CCNE1 ESR1 ESRRA FANCA JUN MAPK14 NR1H4 NR5A1 NR5A2 PBX1 PPARG RARA RARB RARG RORA RXRA SMARCC1 SREBF1 STARD13
Entrez ID		6604
HPRD ID		03440
Ensembl ID		ENSG00000082014
Uniprot IDs		A0A090N8Z9 Q6STE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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