SLC6A2

Description		solute carrier family 6 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Neuronal Cell Body Membrane Presynaptic Membrane Neuron Projection Membrane Raft
	Molecular Function	Actin Binding Neurotransmitter:sodium Symporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Alpha-tubulin Binding Metal Ion Binding Beta-tubulin Binding
	Biological Process	Transport Chemical Synaptic Transmission Monoamine Transport Norepinephrine Transport Response To Pain Dopamine Uptake Involved In Synaptic Transmission Norepinephrine Uptake Transmembrane Transport Neuron Cellular Homeostasis
Pathways		Na+/Cl- dependent neurotransmitter transporters Defective SLC6A2 causes orthostatic intolerance (OI)
Drugs		Amphetamine Phentermine Tramadol Guanadrel Reboxetine Venlafaxine Atomoxetine Amitriptyline Protriptyline Mirtazapine Loxapine Methylphenidate Pethidine Imipramine Duloxetine Dextromethorphan Nortriptyline Amoxapine Mazindol Ergotamine Paroxetine Trimipramine Phenmetrazine Pseudoephedrine Cocaine Maprotiline Diethylpropion Dopamine Sibutramine Chlorphenamine Doxepin Nefazodone Desipramine Bupropion Guanethidine Orphenadrine Escitalopram Ketamine Clomipramine Ephedra Ephedrine Ginkgo biloba MMDA Midomafetamine Dextroamphetamine Methamphetamine Phendimetrazine Nomifensine Amineptine Debrisoquin Bicifadine Milnacipran XEN2174 CRx-119 Mianserin Tapentadol Desvenlafaxine Dexmethylphenidate Levomilnacipran Dosulepin Viloxazine Dasotraline
Diseases		Orthostatic intolerance (OI); Postural tachycardia syndrome (POTS)
GWAS		Birth weight ( 31043758) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		2 interacting genes: PPP2R1A STX1A
Entrez ID		6530
HPRD ID		01232
Ensembl ID		ENSG00000103546
Uniprot IDs		A0A024R6T9 H3BRE9 P23975
PDB IDs
Enriched GO Terms of Interacting Partners?
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